Garcinia cambogia is a kind of tree of the genus Garcinia cambogia of the dicotyledon class, also known as Malabar tamarind, about 20 meters high; the bark is thick and cork-like. Garcinia cambogia is born in the humid jungles of low hillsides, native to India, and also distributed in Southeast Asia. It has been cultivated in abundance in southern India and Thailand for centuries as a fruity herb. The resulting fruit is yellow and has the same name as the plant species. Garcinia cambogia fruits are almost the same size as oranges, and the outer surface is very similar to pumpkin, often with several longitudinal grooves, and the taste is sour. Garcinia cambogia has been used as one of the spice ingredients in curry powder since ancient times. Humans began to study Garcinia Cambogia decades ago, and its active ingredients and structure have gradually become clear, and now it is used as diet food.

The main active ingredient of Garcinia cambogia extract is hydroxycitric acid (HCA) extracted from the peel, and hydroxycitric acid plays a different role in metabolism than citrate and has been proven to accelerate fat metabolism and inhibit fatty acid and cholesterol Synthesis in the human body or organism. Commonly used hydroxycitrate (magnesium salt), can replace citrate in human metabolism to competitively inhibit fatty acid synthesis.

Citrate lyase catalyzes the conversion of citrate to acetyl-CoA, whereas hydroxycitrate has a similar structure to citrate and can competitively inhibit citrate lyase. Citrate lyase is a key enzyme regulating the metabolism of fats, mainly located in the liver. Due to the presence of hydroxycitrate, it will replace citrate and bind to citrate lyase, which has an affinity for hydroxycitrate more than 100 times that of citrate, so citrate can be Completely ignored and not involved in the fatty acid synthesis. As a result, only smaller amounts of acetyl-CoA and malonyl-CoA are formed, with a corresponding reduction in fatty acids.

Therefore Garcinia Cambogia extract helps to stop excess fat accumulation in the body. In addition, body fat absorbs energy through oxidation to produce acetyl-CoA. Hydroxycitrate promotes fat oxidation by inhibiting the production of acetyl-CoA and malonyl-CoA and accelerates the production of acetyl-CoA and malonyl-CoA in adipose tissue.

Garcinia cambogia is noted for its anti-obesity effects. Humans began to study it decades ago, and the active ingredients and structure have gradually become clear, and now it is used as diet food. When people ingest sugars, these sugars are broken down into glucose, carried into muscles, and converted into calories.